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Bellafill® — long-term safety

Posted:9:27 a.m. Monday, Feb. 10, 2014

By Anita Mandal, M.D.

Question: I’m interested in Bellafill® for hollowing cheeks. My doctor says that it has only been studied for about 5 years. How do I know that it will be safe in my tissues 15 years from now?

Answer: Bellafill® has been shown to be very safe long term. It contains PMMA microspheres which stimulate collagen production. These microspheres are not absorbed by the body. Over time, the newly produced collagen fibers wrap around the PMMA spheres to maintain volume and support, for lasting correction.
The PMMA in Bellafill®, also known as polymethylmethacrylate, is a synthetic substance, that has been successfully used medically for 60 years. Well before Bellafill® was developed, PMMA had been used in bone implants, dental surgery and eye implants. It is considered an inert or “non-reactive” substance.
Long term studies 12 to 13 years after treatment have shown that PMMA persists in the body. Even though Bellafill® has been in the U.S. market since 2006, the European version of Bellafill® has been used for much longer and is known to be of lasting duration.
Compared to many injectable fillers like Juvederm, Sculptra and Restylane, the rate of Bellafill® lumps and bumps or granulomas is similar to or lower than that of many temporary fillers. Bellafill® meets the rigorous safety standards of the FDA. It has become one of most popular injectable fillers in my practice.
If you are interested in Bellafill®, a thorough consultation with a Facial Plastic Surgeon who is a qualified Bellafill® specialist, is the first step.

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